Fecal bacteriotherapy- Science

Fecal bacteriotherapy, also known as fecal transfusion, fecal transplant, or human probiotic infusion (HPI), is a medical treatment for patients with pseudomembranous colitis (caused by Clostridium difficile), ulcerative colitis and irritable bowel syndrome which involves restoration of colon homeostasis by reintroducing normal bacterial flora from stool obtained from a healthy donor.

Procedure Description:
The procedure itself involves a 5 to 10 day treatment with enemas, made of bacterial flora from feces of a healthy donor (who needs to be tested for a wide array of bacterial and parasitic agents). The enemas are prepared and administered in a hospital environment to ensure all necessary precautions. The probiotic infusion can also be administered through a nasogastral tube, delivering the bacteria directly to the small intestine.^[1] The two methods can be combined to achieve the best result. Regular checkups are required up to a year following the procedure.

Some Theoretical basis:

The hypothesis behind fecal bacteriotherapy rests on the concept of bacterial interference - using harmless bacteria to displace pathogenic organisms. This approach to combating bacterial infections is not new^[2], and has long been used in animals - for example, to prevent salmonellosis in chickens^[3]. In the case of pseudomembranous colitis the pathogen is known (C. difficile), but since no single pathogen causing ulcerative colitis has been found so far, the effectiveness of fecal bacteriotherapy suggests that the cause of ulcerative colitis may be a previous infection by a still unknown pathogen......

Source: Wikipedia
Read More : http://en.wikipedia.org/wiki/Fecal_bacteriotherapy

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